Two sample MR report
BICDL2_Endothelial Cell (Endo) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 1.8443069 | 11.2213954 | 0.8962947 |
| Weighted median | 3 | 0.0655321 | 0.0355168 | 0.0650229 |
| Inverse variance weighted | 3 | 0.0624935 | 0.0288731 | 0.0304325 |
| Simple mode | 3 | 0.0663373 | 0.0383223 | 0.2255849 |
| Weighted mode | 3 | 0.0663050 | 0.0375340 | 0.2193441 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0088549 | 1 | 0.9250294 |
| Inverse variance weighted | 0.0340684 | 2 | 0.9831101 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -1.252644 | 7.888797 | 0.8997496 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.26e-05 | 0 | TRUE | 0.6522948 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
